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SEP 26, 2013 - Yahoo! News

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Insight: How new cancer drugs can skip randomized trials

By Julie Steenhuysen and Ben Hirschler CHICAGO/LONDON (Reuters) - In 2006 when doctors started testing a melanoma treatment made by Roche Holding AG on patients, they were used to facing slim odds - about one in eight - that the tumors would shrink on chemotherapy. This time, they couldn't believe their eyes. With Zelboraf, a drug that targets specific mutations in cancer cells, eight out of 10 patients in an early-stage trial experienced significant tumor shrinkage. Roche clearly had a remarkable drug, though it only worked for people with a specific genetic makeup. ...

Tags: Insight: How new cancer drugs can skip randomized trials,  Melanoma Latest News